Lipid Nanoparticles
Lipid nanoparticles (LNPs) are versatile, nanoscale delivery vehicles designed to encapsulate and transport therapeutic agents to targeted cells or tissues. They have emerged as crucial tools in the drug delivery and gene therapy fields. Our research teams have pioneered LNP platforms and applications for precise delivery of genetic materials, such as mRNA, to cells. By employing sophisticated engineering techniques, LNPs can be tailored to improve cellular uptake, biodistribution, and therapeutic efficacy. These nanoparticles play a pivotal role in facilitating the intracellular delivery of nucleic acids and small molecules, enhancing treatment outcomes, and enabling the advancement of personalized medicine. LNPs can effectively replace conventional delivery methods, offering a more efficient and targeted approach to treating a wide range of diseases.
Molecular detection platform for payload distribution and capacity of mRNA lipid nanoparticles.
Payload Distribution and Capacity of mRNA Lipid Nanoparticles
High-throughput screening of lipid nanoparticles for tissue-targeted gene expression.
Multi-step Screening of DNA/lipid Nanoparticles and Co-delivery with siRNA to Enhance and Prolong Gene Expression
Lipid nanoparticle optimization for modulation of the immune activity of helper T cells towards enhanced antitumour activity.
Screening for Lipid Nanoparticles that Modulate the Immune Activity of Helper T cells Towards Enhanced Antitumour Activity