The immunoengineering field is transforming cancer, autoimmunity, regeneration, and transplantation treatments by combining the diverse and complex fields of engineering and immunology. There is a significant need to train engineers in immunology and immunologists in quantitative engineering techniques. Moreover, there is a need to bridge basic immunological discoveries with advances in clinical application. This virtual workshop will review immune system fundamentals and components, engineering strategies to modulate the immune system, and clinical applications.
After attending this workshop, the learner will demonstrate the ability to:
– Review the fundamentals and recent discoveries in the function of the immune system.
– Identify engineering strategies to manipulate the immune system.
– Describe the clinical applications of immunoengineering.
The workshop is designed for graduate students, medical students, residents, and fellows in engineering, immunology, and related fields. Engineering and clinical faculty, and industry members will benefit from the course as well.
Dates and Time
Every Tuesday and Thursday, January 4 – 27, 2022, from 4:00 pm – 5:30 pm ET.
You only need to register once to attend all dates. Registration is allowed at any time.
This workshop is eligible for CME credit and offered as a two-credit course for Johns Hopkins students. The course is listed as EN.580.543 (for undergraduate students) and EN.580.843 (for graduate students) Independent Study: Advances in Immunoengineering in SIS. Students need to register for the course and the workshop.
Week 1 – T-Cell Engineering and Immunometabolism
|Tuesday, January 4, 2022||Thursday, January 6, 2022|
T Cell Therapy of Cancer: the New Math
Modulating Antigen-specific CD8 T Cell Differentiation for Immunotherapy of Cancer
|Kellie N. Smith
Integrated Multi-Omics for Tumor-Reactive T Cell Profiling
Mitochondrial Shape-Shifting in the CD4+ T Cell Response
Week 2 – Regenerative Immunology and T Cell Programming
|Tuesday, January 11, 2022||Thursday, January 13, 2022|
Immunoengineering … Finally!
Metabolic Reprogramming to Improve T Cell Function
Immune Changes with Aging and Implications for Regenerative Medicine
Engineering Artificial Antigen Presenting Cells, aAPC, for Cancer Immunotherapy: From Bench to Bedside
Week 3 – Immunotherapy, Vaccine, and Autoimmunity
|Tuesday, January 18, 2022||Thursday, January 20, 2022|
Creating Living Drugs with Synthetic Compounds
Systemic Delivery of a Nanoparticle Neoantigen Cancer Vaccine Generates Effective Antitumor Immunity Through CD8+ T Cells and Innate Stimulation
Decoding Immunity Using Engineered Immune Organoids
In Vivo Re-programming of Autoantigen-experienced T-follicular Helper Cells for the Treatment of Autoimmunity
Week 4 – Immunoengineering, Tissue Context, and Immunotherapies
|Tuesday, January 25, 2022||Thursday, January 27, 2022|
Biomaterials for T Cell Immunity
Localized Adaptation and Tissue Residence of Immune Cells
Tracking the Human Alloresponse in Transplant Recipients
Immunity to SARS-CoV-2 Vaccination