Hai-Quan Mao and his collaborators at Johns Hopkins conduct NIH-funded materials science research using mRNA and other advances to address urgent medical challenges like cancer, malaria, and nerve and tissue damage RNA medicine shows promise for training the body to recognize tumors and eliminate them, but a better delivery system is needed to activate the immune cells within the body and generate an anti-tumor response. With backing from the...

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Story by Johns Hopkins Medicine. A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine. Searching for subtypes of immune cells seen only in the most serious, grade 4 brain tumors,...

Federal funding is enabling biomedical engineer Jamie Spangler and her team at Johns Hopkins to develop innovative treatments for autoimmune disorders, cancer, and other complex diseases Jamie Spangler oversees a lab of 33 scientists at Johns Hopkins who are developing new, targeted treatments that harness the power of the immune system. With the backing of the National Institutes of Health, Spangler and her team use the body's natural...

Jordan Green, the Herschel L. Seder Professor of Biomedical Engineering, is among sixteen Hopkins faculty members selected, out of 135 applicants, for the inaugural cohort for the Provost’s Fellows for Public Engagement. The fellows will take part in a yearlong program designed to build their public engagement skills across a range of media platforms and audiences. Green currently serves as the vice chair for research and translation in...

Mary Omotoso, a biomedical engineering PhD student, was a 2024 inductee into the university’s chapter of the Edward A. Bouchet Graduate Honor Society. The Bouchet Society honors Edward Alexander Bouchet, who in 1876 became the first African American doctoral recipient in the United States. The society seeks to develop a network of pre-eminent scholars who exemplify academic and personal excellence, foster environments of support, and serve as...

The Johns Hopkins Center for Translational ImmunoEngineering, or JH-TIE, recently earned $6.4 million in continued funding over the next five years from the NIH’s National Institute of Biomedical Imaging and Bioengineering (NIBIB). The grant is part of  NIBIB’s  National Centers for Biomedical Imaging and Bioengineering (NCBIB) program, and JH-TIE is the program’s first center to focus on immunoengineering. The grant is...

Immunoengineering research by Johns Hopkins biomedical engineers and JH-TIE researcher was recently featured on the cover of the journal JCI Insight. The article, “Engineered cytokine/antibody fusion proteins improve IL-2 delivery to pro-inflammatory cells and promote antitumor activity,” was selected and featured as the cover for the September 2024 issue. The cover art was illustrated by Ann Seliger, a recent graduate of the Medical...

Si-Sam Kang, fourth year PhD student receives PhRMA Foundation Predoctoral Fellowship in drug delivery to improve adoptive cell therapy. Read the full story by...