Tools

Our increasing comprehension of immunity has shown that this system is deeply enmeshed in many aspects of physiology, with complex and often contradictory outcomes. This growing knowledge offers an expanding domain of opportunities, and challenges, to use and exploit these powerful components within the immune system itself and a broader health context. JH-TIE is focused on developing novel composition of matter tools for immunomodulation, as well as protocols for their use and wide-scale implementation. The tools and technology we develop will catalyze advances in cellular engineering technologies to specifically modulate the immune system, with broad applications to human health. 

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Abstract graphic of an immune cell in blue with purple aAPCs on it's surface.

Artificial Antigen
Presenting Cells

Ai generated graphic of a tumor and its microenvironment. The tumor is in blue and is surrounded by red vessels and yellow nanoparticle.

Polymeric Nanomaterials

Blue, orange, and gray graphic of engineered cytokine protein.

Engineered Proteins

Graphic design of DNA encapsulated of within liposomes. The background is black, the liposome is yellow, and the DNA is purple.

Lipid Nanoparticles

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Code

Protocols and Videos